I will tell some troubleshooting steps to you tomorrow.
For a quick test, can you make a shortcut of the Simucube Configuration Tool.exe with a parameter log at the end. Then it will write a log.txt file.
For example, the log parameter would look like this on my shortcut:
"C:\Users\mikat\Downloads\simucube_fw_open_beta_0.50.3\Simucube Configuration Tool.exe" log